The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 06, 2024

Filed:

May. 16, 2018
Applicants:

Exosome Diagnostics, Inc., Waltham, MA (US);

The Brigham and Women's Hospital, Boston, MA (US);

Inventors:

James Hurley, Marblehead, MA (US);

Christine Coticchia, Waltham, MA (US);

Robert Kitchen, Somerville, MA (US);

Vasisht Tadigotla, Newton, MA (US);

Johan Karl Olov Skog, Lincoln, MA (US);

Jamil Azzi, Boston, MA (US);

Assignees:

Exosome Diagnostics, Inc., Waltham, MA (US);

The Brigham and Women's Hospital, Boston, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6883 (2018.01); G01N 1/28 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); C12Q 2600/158 (2013.01); G01N 1/28 (2013.01); G01N 33/6893 (2013.01); G01N 2800/245 (2013.01); G01N 2800/347 (2013.01);
Abstract

The invention relates generally to the use of microvesicle biomarkers such as nucleic acids, including nucleic acid signatures, and/or proteins for assessing a kidney transplant rejection in a patient. The invention further relates to assessing, and/or to monitoring kidney transplant rejection in patients who have received a renal transplant.


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