The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2024
Filed:
Apr. 05, 2019
Applicant:
The General Hospital Corporation, Boston, MA (US);
Inventors:
Jae Keith Joung, Winchester, MA (US);
Eric M. Mendenhall, Madison, AL (US);
Bradley E. Bernstein, Cambridge, MA (US);
Deepak Reyon, Malden, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/02 (2006.01); C07K 14/195 (2006.01); C12N 9/06 (2006.01); C12N 9/22 (2006.01); A61K 38/00 (2006.01); C12N 15/63 (2006.01); C12N 5/10 (2006.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C12N 9/0004 (2013.01); C07K 14/195 (2013.01); C12N 9/0026 (2013.01); C12N 9/0083 (2013.01); C12N 9/22 (2013.01); C12Y 105/00 (2013.01); C12Y 114/99 (2013.01); A61K 38/00 (2013.01); C07K 2319/80 (2013.01); C12N 15/1093 (2013.01); C12N 15/63 (2013.01);
Abstract
Fusion proteins comprising a DNA binding domain, e.g., a TAL effector repeat array (TALE) or zinc finger array, and a catalytic domain comprising a sequence that catalyzes histone demethylation, and methods of use thereof.