The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2024
Filed:
Mar. 27, 2023
Applicant:
Genecraft Inc., Cheongju-si, KR;
Inventors:
Suk Chul Bae, Cheongju-si, KR;
You Soub Lee, Cheongju-si, KR;
Xinzi Chi, Cheongju-si, KR;
Tae Geun Park, Cheongju-si, KR;
Woo-Jin Kim, Seoul, KR;
Assignee:
GENECRAFT INC., Cheongju-si, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/01 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); C12N 2750/14143 (2013.01); C12N 2750/14145 (2013.01);
Abstract
Described herein is an adeno-associated virus (AAV) complex platform including an asymmetrically modified inverted terminal repeat (ITR). The AAV complex has advantages of increased productivity and expression efficiency of a transgene, and decreased genotoxicity, by having an asymmetric ITR in which any one of two ITRs is modified. Also, described herein is a composition comprising the adeno-associated virus complex and a method of gene therapy.