The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2024
Filed:
May. 09, 2018
Applicants:
Vib Vzw, Ghent, BE;
Universiteit Gent, Ghent, BE;
Inventors:
Nico Callewaert, Nevele, BE;
Bram Laukens, Ghent, BE;
Loes Van Schie, Ghent, BE;
Wander Van Breedam, Antwerp, BE;
Wim Nerinckx, Astene, BE;
Assignees:
VIB VZW, Ghent, BE;
Universiteit Gent, Ghent, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); A61K 47/68 (2017.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); A61K 47/6871 (2017.08); C07K 2317/22 (2013.01); C07K 2317/41 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01); C07K 2317/569 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract
The present invention provides nucleotide sequences encoding polypeptides comprising immunoglobulin variable domains with engineered glycosylation acceptor sites. Specifically, the invention provides immunoglobulin variable domain proteins modified with selected glycans and specific glycan-conjugates thereof. Also provided herein are methods for the production of glycosylated immunoglobulin variable domains and glycan-conjugates thereof.