The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 06, 2024

Filed:

May. 24, 2019
Applicant:

Abl Bio Inc., Seongnam-si, KR;

Inventors:

Kyeongsu Park, Seongnam-si, KR;

Yangsoon Lee, Seongnam-si, KR;

Hyejin Chung, Seongnam-si, KR;

Uijung Jung, Seongnam-si, KR;

Yong-Gyu Son, Seongnam-si, KR;

Sang-Jun Ha, Seongnam-si, KR;

Myeong Joon Kim, Seongnam-si, KR;

Eunyoung Park, Seongnam-si, KR;

Kyungjin Park, Seongnam-si, KR;

Eunsil Sung, Seongnam-si, KR;

Yeunju Kim, Seongnam-si, KR;

Jinhyung Ahn, Seongnam-si, KR;

Byungje Sung, Seongnam-si, KR;

Daehae Song, Seongnam-si, KR;

Youngdon Pak, Seongnam-si, KR;

Assignee:

ABL BIO INC., Seongnam-si, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); G01N 33/574 (2006.01); A61P 35/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2827 (2013.01); A61P 35/00 (2018.01); G01N 33/57492 (2013.01); A61K 2039/505 (2013.01); C07K 2317/33 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/732 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); G01N 2333/70532 (2013.01);
Abstract

Provided is an anti-B7-H3 antibody specifically recognizing a B7-H3, which can be usefully as a cancer therapeutic agent, as having an inhibitory activity of an immune checkpoint which induces antibody-dependent cell-mediated cytotoxicity and T cell activation inhibited by B7-H3. In particular, the antibody having the inhibitory activity of an immune checkpoint can be used in combination with other immunoantibody therapeutic agents. In addition, it can be usefully used for cancer targeting treatment including detection of various cancers expressing B7-H3 through specific binding to B7-H3, and drug delivery to specific cancer, etc.


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