The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 06, 2024

Filed:

Dec. 21, 2018
Applicants:

The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);

The United States Government As Represented BY the Department of Veterans Affairs, Washington, DC (US);

Inventors:

Anton Wyss-Coray, Palo Alto, CA (US);

John Vincent Pluvinage, Atherton, CA (US);

Michael C. Bassik, Stanford, CA (US);

Michael Haney, Stanford, CA (US);

Benjamin Smith, Stanford, CA (US);

Carolyn Bertozzi, Stanford, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61P 25/28 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01); A61K 38/47 (2006.01); C12N 9/24 (2006.01); A61K 47/68 (2017.01); A61M 25/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); A61K 38/47 (2013.01); A61K 39/001113 (2018.08); A61K 39/3955 (2013.01); A61K 47/6815 (2017.08); A61K 47/6849 (2017.08); A61P 25/28 (2018.01); C12N 9/2402 (2013.01); C12Y 302/01018 (2013.01); A61K 2039/505 (2013.01); A61M 25/0097 (2013.01); C07K 2317/76 (2013.01); C07K 2317/77 (2013.01);
Abstract

Provided herein are compositions, methods, kits and systems for treating cells, tissues and subjects to alter age-related biology (e.g., to study or to treat age-related diseases and conditions). In particular, provided herein are compositions, methods, and uses for inhibition or modification of sialic acid or its cognate receptor to restore phagocytosis in aged cells.


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