The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2024
Filed:
Feb. 12, 2021
Applicants:
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Inventors:
E. James Petersson, Wynnewood, PA (US);
Alan Saghatelian, Somerville, MA (US);
Assignees:
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, Philadelphia, PA (US);
PRESIDENT AND FELLOWS OF HARVARD COLLEGE, Cambridge, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/605 (2006.01); A61K 9/00 (2006.01); A61K 38/26 (2006.01); C07K 1/113 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/605 (2013.01); A61K 9/0019 (2013.01); A61K 38/26 (2013.01); C07K 1/1136 (2013.01); A61K 38/00 (2013.01);
Abstract
The invention includes a thioamide-modified peptide, wherein the thioamide modification increases the in vivo half-life of the peptide. The invention further includes methods of treating or preventing a disease or disorder in a subject in need thereof, the method comprising administering to the subject a thioamide-modified peptide of the invention.