The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2024
Filed:
Apr. 16, 2019
Hangzhou Sumgen Biotech Co., Ltd., Zhejiang, CN;
Sumgen Mab (Beijing) Biotech Co., Ltd., Beijing, CN;
Ming Lv, Zhejiang, CN;
Xiaoran Ding, Zhejiang, CN;
Shiwei Miao, Zhejiang, CN;
Bin Tan, Zhejiang, CN;
Xuegong Wang, Zhejiang, CN;
HANGZHOU SUMGEN BIOTECH CO., LTD., Zhejiang, CN;
SUMGEN MAB (BEIJING) BIOTECH CO., LTD., Beijing, CN;
Abstract
Provided by the present invention are a fusion protein binding to a CD47 protein and an application thereof, wherein the fusion protein is capable of binding to a CD47 protein by using a KD value of 1×10M or lower. The fusion protein may specifically block the interaction between a CD47 protein and SIRPα without causing a blood coagulation reaction, and may further inhibit the growth and/or proliferation of tumors or tumor cells.