The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 06, 2024

Filed:

Dec. 26, 2018
Applicants:

St. Jude Children's Research Hospital, Inc., Memphis, TN (US);

Coa Therapeutics, Inc., San Francisco, CA (US);

Inventors:

Richard E. Lee, Cordova, TN (US);

Rajendra P. Tangallapally, Collierville, TN (US);

Charles O. Rock, Bartlett, TN (US);

Suzanne Jackowski, Bartlett, TN (US);

Anne V. Edwards, Memphis, TN (US);

Mi Kyung Yun, Collierville, TN (US);

Chitra Subramanian, Cordova, TN (US);

Robert Zamboni, Beaconsfield, CA;

T. Jagadeeswar Reddy, Pierrefonds, CA;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/04 (2006.01); A61K 31/197 (2006.01);
U.S. Cl.
CPC ...
C07D 403/04 (2013.01); A61K 31/197 (2013.01);
Abstract

The present disclosure relates to chemical compounds that modulate pantothenate kinase (PanK) activity for the treatment of metabolic disorders (such as diabetes mellitus type II), neurologic disorders (such as pantothenate kinase-associated neurodegeneration), pharmaceutical compositions containing such compounds, and their use in treatment. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.


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