The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2024
Filed:
Jan. 29, 2021
Translate Bio, Inc., Lexington, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Michael Heartlein, Lexington, MA (US);
Daniel Anderson, Cambridge, MA (US);
Yizhou Dong, Cambridge, MA (US);
Frank DeRosa, Lexington, MA (US);
Translate Bio, Inc., Waltham, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Abstract
The present invention provides, among other things, methods of delivering mRNA in vivo, including administering to a subject in need of delivery a composition comprising an mRNA encoding a protein, encapsulated within a liposome such that the administering of the composition results in the expression of the protein encoded by the mRNA in vivo, wherein the liposome comprises a cationic lipid of formula I-c: or a pharmaceutically acceptable salt thereof.