The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 06, 2024

Filed:

Jul. 28, 2021
Applicant:

Sun Pharma Advanced Research Company Limited, Mumbai, IN;

Inventors:

Ajay Jaysingh Khopade, Baroda, IN;

Arindam Halder, Baroda, IN;

Ankit Shaileshkumar Shah, Baroda, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/573 (2006.01); A61K 9/08 (2006.01); A61K 47/18 (2017.01); A61K 47/32 (2006.01); A61K 47/44 (2017.01); A61P 27/02 (2006.01); A61P 27/04 (2006.01); A61K 9/00 (2006.01); A61K 47/02 (2006.01);
U.S. Cl.
CPC ...
A61K 9/08 (2013.01); A61K 9/0048 (2013.01); A61K 31/573 (2013.01); A61K 47/02 (2013.01); A61K 47/186 (2013.01); A61K 47/32 (2013.01); A61K 47/44 (2013.01); A61P 27/02 (2018.01); A61P 27/04 (2018.01);
Abstract

The present invention provides a method of treatment of inflammatory disorder of the eye, said method comprising administering into the eye of a person in need thereof, an aqueous solution comprising difluprednate as the sole active ingredient at a concentration of 0.02% to 0.04% weight by volume in an aqueous vehicle, wherein the solution is free of oil and wherein the solution is administered twice-a-day. The present invention also provides an ophthalmic solution comprising a. therapeutically effective concentration of difluprednate, a crystal growth inhibitor and pharmaceutically acceptable amounts of a solubilizer comprising a mixture of i. quaternary ammonium compound and ii. polyethoxylated castor oil, b. in an aqueous vehicle. wherein the crystal growth inhibitor is polyvinyl alcohol or its derivatives.


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