The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2024
Filed:
May. 01, 2020
Applicant:
The Board of Regents of the University of Texas System, Austin, TX (US);
Inventors:
Sean Morrison, Dallas, TX (US);
Rui Yue, Dallas, TX (US);
Assignee:
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); A61P 19/08 (2006.01); A61K 38/29 (2006.01); A61K 45/06 (2006.01); A61P 35/04 (2006.01); A61P 19/10 (2006.01);
U.S. Cl.
CPC ...
A61K 38/18 (2013.01); A61K 38/29 (2013.01); A61K 45/06 (2013.01); A61P 19/08 (2018.01); A61P 19/10 (2018.01); A61P 35/04 (2018.01);
Abstract
The present disclosure describes the C-type lectin CLEC11a as a bone growth factor. Clec11a-deficient mice showed reduced bone volume and mineralization, while bone resorption remained unchanged. Administration of recombinant Clec11a systemically promoted bone formation in mice at risk for osteoporosis.