The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2024
Filed:
Sep. 25, 2019
Applicant:
Janssen Biotech, Inc., Horsham, PA (US);
Inventor:
Jean Xu, Raritan, NJ (US);
Assignee:
Janssen Biotech, Inc., Horsham, PA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/39 (2015.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
A61K 35/39 (2013.01); C12N 5/0676 (2013.01); C12N 2500/34 (2013.01); C12N 2501/115 (2013.01); C12N 2501/12 (2013.01); C12N 2501/155 (2013.01); C12N 2501/16 (2013.01); C12N 2501/21 (2013.01); C12N 2501/23 (2013.01); C12N 2501/335 (2013.01); C12N 2501/385 (2013.01); C12N 2501/40 (2013.01); C12N 2501/415 (2013.01); C12N 2501/42 (2013.01); C12N 2501/70 (2013.01); C12N 2501/999 (2013.01); C12N 2506/02 (2013.01); C12N 2533/90 (2013.01);
Abstract
The present invention provides methods to promote the differentiation of pluripotent stem cells. In particular, the present invention provides an improved method for the formation of pancreatic endoderm, pancreatic hormone expressing cells and pancreatic hormone secreting cells. The present invention also provides methods to promote the differentiation of pluripotent stem cells without the use of a feeder cell layer.