The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2024
Filed:
Dec. 11, 2017
Applicant:
Miltenyi Biotec Gmbh, Bergisch Gladbach, DE;
Inventors:
Assignee:
Miltenyi Biotec B.V. & Co. KG, Bergisch Gladbach, DE;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/15 (2015.01); C07K 14/705 (2006.01); C07K 14/725 (2006.01); A61K 35/17 (2015.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
A61K 35/15 (2013.01); C07K 14/7051 (2013.01); C07K 14/70507 (2013.01); C07K 14/70517 (2013.01); C07K 14/70521 (2013.01); C07K 16/2887 (2013.01); C07K 16/3053 (2013.01); C12N 5/0638 (2013.01); A61K 35/17 (2013.01); C07K 2317/31 (2013.01); C07K 2317/622 (2013.01); C07K 2319/03 (2013.01); C07K 2319/33 (2013.01); C12N 2510/00 (2013.01); C12N 2740/16043 (2013.01);
Abstract
The present invention provides an immune effector cell that comprises a chimeric antigen receptor (CAR) specific for a tag of a tagged polypeptide, wherein said polypeptide binds to an antigen of a target cell, and a chimeric costimulatory receptor (CCR) specific for a further antigen. The CCR is not able to mediate said immune response on its own but boosts the immune response of said immune effector cell triggered by the CAR.