The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 06, 2024
Filed:
Jan. 25, 2022
Applicant:
Brii Biosciences, Inc., Durham, NC (US);
Inventors:
Lianhong Xu, Durham, NC (US);
Zhi Hong, Durham, NC (US);
Assignee:
Brii Biosciences, Inc., Durham, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/70 (2006.01); A01N 43/04 (2006.01); A61K 31/7076 (2006.01); A61K 45/06 (2006.01); A61P 31/18 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7076 (2013.01); A61K 45/06 (2013.01); A61P 31/18 (2018.01);
Abstract
The present disclosure is directed to methods of treating or preventing RNA virus infections and retroviral diseases, such as HIV and AIDS, comprising administering to a subject in need an effective amount of (a) a capsid inhibitor and (b) an adenosine derivative disclosed herein. Compositions comprising an effective amount of an adenosine derivative and an effective amount of a capsid (CA) inhibitor are also provided.