The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2024
Filed:
Nov. 27, 2019
Applicant:
Bioscreening & Diagnostics Llc, Detroit, MI (US);
Inventor:
Ray Bahado-Singh, Grosse Pointe Shores, MI (US);
Assignee:
Bioscreening & Diagnostics LLC, Detroit, MI (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/6883 (2018.01); G16B 20/20 (2019.01); G16B 40/00 (2019.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); G16B 20/20 (2019.02); G16B 40/00 (2019.02); C12Q 2600/112 (2013.01); C12Q 2600/154 (2013.01);
Abstract
The present disclosure describes significant methylation changes in multiple genes and multiple metabolites in body fluid in response to TBI. Gene pathways affected included several known to be involved in neurological and brain function. A large number of good to excellent biomarkers for the detection of TBI was identified. The combination of epigenomic, clinical and metabolomic markers in different combinations overall were highly accurate for the detection of pediatric concussion using Artificial Intelligence-based techniques.