The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2024
Filed:
Mar. 05, 2021
Applicant:
Verinata Health, Inc., Redwood City, CA (US);
Inventors:
Richard P. Rava, Redwood City, CA (US);
Manjula Chinnappa, Foster City, CA (US);
David A. Comstock, Sunnyvale, CA (US);
Gabrielle Heilek, Mountain View, CA (US);
Brian Kent Rhees, Chandler, AZ (US);
Assignee:
VERINATA HEALTH, INC., Redwood City, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6869 (2018.01); C12Q 1/6806 (2018.01); C12Q 1/6809 (2018.01); G16B 30/10 (2019.01); G16B 20/10 (2019.01); G16H 10/40 (2018.01); C12Q 1/6883 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6869 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/6809 (2013.01); G16B 20/10 (2019.02); G16B 30/10 (2019.02); G16H 10/40 (2018.01); C12Q 1/6883 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/112 (2013.01);
Abstract
The invention provides methods for determining aneuploidy and/or fetal fraction in maternal samples comprising fetal and maternal cfDNA by massively parallel sequencing. The method comprises a novel protocol for preparing sequencing libraries that unexpectedly improves the quality of library DNA while expediting the process of analysis of samples for prenatal diagnoses.