The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2024
Filed:
Nov. 19, 2019
Applicant:
President and Fellows of Harvard College, Cambridge, MA (US);
Inventors:
Donald E. Ingber, Boston, MA (US);
Hyun Jung Kim, Brookline, MA (US);
Assignee:
PRESIDENT AND FELLOWS OF HARVARD COLLEGE, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12M 3/00 (2006.01); B01L 3/00 (2006.01); C12N 5/071 (2010.01); C12M 1/12 (2006.01); C12N 1/20 (2006.01); C12M 1/42 (2006.01); C12N 1/14 (2006.01); C12M 1/24 (2006.01); C12M 1/00 (2006.01); C12M 1/06 (2006.01); C12M 1/34 (2006.01); C12N 5/074 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0697 (2013.01); C12M 21/08 (2013.01); C12M 23/08 (2013.01); C12M 23/20 (2013.01); C12M 23/26 (2013.01); C12M 23/34 (2013.01); C12M 23/38 (2013.01); C12M 25/02 (2013.01); C12M 27/02 (2013.01); C12M 29/04 (2013.01); C12M 29/06 (2013.01); C12M 35/04 (2013.01); C12M 35/08 (2013.01); C12M 41/12 (2013.01); C12M 41/26 (2013.01); C12M 41/40 (2013.01); C12M 41/44 (2013.01); C12N 1/14 (2013.01); C12N 1/20 (2013.01); C12N 5/068 (2013.01); C12N 5/0679 (2013.01); C12N 5/0696 (2013.01);
Abstract
The embodiments of the invention described herein relate to systems and methods for culturing and/or maintaining intestinal cells, tissues and/or organoids in vitro. The cells, tissues and/or organoids cultured according to the methods and systems described herein can mimic or reproduce natural intestinal epithelial structures and behavior as well as support co-culture of intestinal microflora.