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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11884935 B1

PDFFull Text
Date of Patent:
Jan. 30, 2024

Filed:

Jun. 28, 2019

Method for inducing trans-differentiation of cardiomyocytes based on exosome

Applicant:

Korea Institute of Science and Technology, Seoul, KR;

Inventors:

Ick Chan Kwon, Seoul, KR;

Sun Hwa Kim, Seoul, KR;

Yoosoo Yang, Seoul, KR;

Hyosuk Kim, Seoul, KR;

Assignee:

KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, Seoul, KR;

Attorney:

Birch, Stewart, Kolasch & Birch, LLP

Primary Examiner:

Anoop K Singh

Assistant Examiner:

Suzanne E Ziska

Int. Cl.
CPC ...
C12N 5/077 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0657 (2013.01); C12N 2500/30 (2013.01); C12N 2500/32 (2013.01); C12N 2500/38 (2013.01); C12N 2501/235 (2013.01); C12N 2501/33 (2013.01); C12N 2506/02 (2013.01);
Abstract

The present invention relates to a method for inducing trans-differentiation of cardiomyocytes based on exosome, and more particularly, to a method for inducing trans-differentiation of a fibroblast into a cardiomyocyte, comprising the steps of: isolating exosomes in a culture medium during a process of differentiating a stem cell into the cardiomyocyte; culturing a fibroblast in a cardiomyocyte reprogramming medium containing the isolated exosomes; and culturing the fibroblast cultured in a cardiomyocyte differentiation medium containing the isolated exosomes.

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Kwon, Ick. (2024). Method for inducing trans-differentiation of cardiomyocytes based on exosome (U.S. Patent No. 11884935). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11884935

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