The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2024
Filed:
Dec. 31, 2020
Applicant:
Celgene Quanticel Research, Inc., San Diego, CA (US);
Inventor:
Amogh Boloor, San Diego, CA (US);
Assignee:
Celgene Quanticel Research, Inc., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/04 (2006.01); C07D 217/24 (2006.01); C07D 413/04 (2006.01); C07D 401/04 (2006.01); C07D 471/04 (2006.01); C07D 405/04 (2006.01); C07D 487/04 (2006.01); C07D 211/94 (2006.01); C07D 401/14 (2006.01); C07D 213/64 (2006.01); C07D 213/73 (2006.01); C07D 213/74 (2006.01); C07D 237/14 (2006.01); C07D 239/54 (2006.01); C07D 239/56 (2006.01); C07D 241/20 (2006.01); C07D 403/04 (2006.01); C07D 405/12 (2006.01); C07D 409/04 (2006.01); C07D 413/06 (2006.01); C07D 417/14 (2006.01); C07D 491/048 (2006.01); C07D 495/04 (2006.01); C07D 213/69 (2006.01); C07D 213/70 (2006.01); C07D 401/12 (2006.01); C07D 405/06 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); C07D 211/94 (2013.01); C07D 213/64 (2013.01); C07D 213/69 (2013.01); C07D 213/70 (2013.01); C07D 213/73 (2013.01); C07D 213/74 (2013.01); C07D 217/24 (2013.01); C07D 237/14 (2013.01); C07D 239/54 (2013.01); C07D 239/56 (2013.01); C07D 241/20 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 405/04 (2013.01); C07D 405/06 (2013.01); C07D 405/12 (2013.01); C07D 409/04 (2013.01); C07D 413/04 (2013.01); C07D 413/06 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 491/048 (2013.01); C07D 495/04 (2013.01);
Abstract
The present invention relates to substituted heterocyclic derivative compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of cancer and neoplastic disease.