The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2024
Filed:
May. 13, 2020
Vertex Pharmaceuticals Incorporated, Boston, MA (US);
Upul Keerthi Bandarage, Lexington, MA (US);
Cavan McKeon Bligh, Melrose, MA (US);
Diane Boucher, South Hamilton, MA (US);
Michael John Boyd, Sharon, MA (US);
Michael Aaron Brodney, Newton, MA (US);
Michael Philip Clark, Concord, MA (US);
Veronique Damagnez, Boston, MA (US);
Lev Tyler Dewey Fanning, San Marcos, CA (US);
Robert Francis Fimognari, Brookline, MA (US);
Gabrielle Simone Fleming, Boston, MA (US);
Kevin James Gagnon, Burlington, MA (US);
Pedro Manuel Garcia Barrantes, Melrose, MA (US);
Robert Daniel Giacometti, Malden, MA (US);
Simon Giroux, Cambridge, MA (US);
Ronald Lee Grey, Jr., Mansfield, MA (US);
Samantha Guido, Quincy, MA (US);
Amy Beth Hall, Wellesley Hills, MA (US);
Sarah Carol Hood, Worcester, MA (US);
Dennis James Hurley, San Marcos, CA (US);
Mac Arthur Johnson, Jr., Derry, NH (US);
Peter Jones, Sharon, MA (US);
Sarathy Kesavan, Quincy, MA (US);
Mei-Hsiu Lai, Waltham, MA (US);
Siying Liu, Malden, MA (US);
Adam Looker, Newtonville, MA (US);
Brad Maxwell, Holliston, MA (US);
John Patrick Maxwell, Hingham, MA (US);
Ales Medek, Winchester, MA (US);
Philippe Marcel Nuhant, Dorchester, MA (US);
Kirk Alan Overhoff, Lynn, MA (US);
Setu Roday, Arlington, MA (US);
Stefanie Roeper, Medford, MA (US);
Steven M. Ronkin, Watertown, MA (US);
Rupa Sawant, Wayland, MA (US);
Yi Shi, Natick, MA (US);
Muna Shrestha, Belmont, MA (US);
Marisa Sposato, Cambridge, MA (US);
Kathy Stavropoulos, Quincy, MA (US);
Rebecca Jane Swett, Somerville, MA (US);
Timothy Lewis Tapley, Cardiff, CA (US);
Qing Tang, Boxborough, MA (US);
Stephen Thomson, Del Mar, CA (US);
Jinwang Xu, Framingham, MA (US);
Mariam Zaky, Boston, MA (US);
Kevin Michael Cottrell, Cambridge, MA (US);
Vertex Pharmaceuticals Incorporated, Boston, MA (US);
Abstract
The disclosure provides compounds useful for treating alpha-1 antitrypsin deficiency (AATD), according to formula (I): tautomers thereof, pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable salts of the tautomers, deuterated derivatives of the compounds, deuterated derivatives of the tautomers, and deuterated derivatives of the salts, solid forms of those compounds and processes for making those compounds.