The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 30, 2024

Filed:

May. 18, 2021
Applicant:

Roche Sequencing Solutions, Inc., Pleasanton, CA (US);

Inventors:

Roger J. A. Chen, Saratoga, CA (US);

Randy Davis, Pleasanton, CA (US);

Assignee:

Roche Sequencing Solutions, Inc., Pleasanton, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B29C 67/20 (2006.01); B82Y 5/00 (2011.01); C12Q 1/6869 (2018.01); G01N 33/487 (2006.01); B82Y 10/00 (2011.01); B82Y 40/00 (2011.01);
U.S. Cl.
CPC ...
B29C 67/20 (2013.01); B82Y 5/00 (2013.01); C12Q 1/6869 (2013.01); G01N 33/48721 (2013.01); B82Y 10/00 (2013.01); B82Y 40/00 (2013.01); Y10S 977/797 (2013.01); Y10S 977/90 (2013.01); Y10S 977/942 (2013.01);
Abstract

Techniques for forming a nanopore in a lipid bilayer are described herein. In one example, an agitation stimulus level such as an electrical agitation stimulus is applied to a lipid bilayer wherein the agitation stimulus level tends to facilitate the formation of nanopores in the lipid bilayer. In some embodiments, a change in an electrical property of the lipid bilayer resulting from the formation of the nanopore in the lipid bilayer is detected, and a nanopore has formed in the lipid bilayer is determined based on the detected change in the lipid bilayer electrical property.


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