The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2024
Filed:
May. 20, 2021
Applicant:
Mirror Biologics, Inc., Mesa, AZ (US);
Inventor:
Michael Har-Noy, Jerusalem, IL;
Assignee:
Mirror Biologics, Inc., Wesley Chapel, FL (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/39 (2006.01); A61K 38/20 (2006.01); A61K 38/19 (2006.01); A61K 38/21 (2006.01); A61K 39/085 (2006.01); A61K 38/17 (2006.01); A61K 35/17 (2015.01); C12N 5/0783 (2010.01); A61K 39/385 (2006.01); A61K 39/44 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39 (2013.01); A61K 35/17 (2013.01); A61K 38/177 (2013.01); A61K 38/19 (2013.01); A61K 38/20 (2013.01); A61K 38/21 (2013.01); A61K 39/085 (2013.01); A61K 39/385 (2013.01); A61K 39/44 (2013.01); C12N 5/0637 (2013.01); A61K 2039/5158 (2013.01); A61K 2039/55516 (2013.01); A61K 2039/55522 (2013.01); A61K 2039/55527 (2013.01); A61K 2039/55533 (2013.01); A61K 2039/57 (2013.01);
Abstract
The present invention relates to compositions and methods that promote the induction of IL-12 in a patient. The composition includes activated allogeneic cells that are administered to a patient with a disease such as cancer. Administration of the composition skews the patient's immune response to a Th1 environment and produces detectable levels of IL-12 in the patient's plasma, without any IL-12 related toxicity.