The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 30, 2024

Filed:

Dec. 19, 2018
Applicant:

University of the Witwatersrand, Johannesburg, Johannesburg, ZA;

Inventors:

Pradeep Kumar, Johannesburg, ZA;

Viness Pillay, Johannesburg, ZA;

Yahya Essop Choonara, Johannesburg, ZA;

Girish Modi, Johannesburg, ZA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/39 (2006.01); A61K 47/58 (2017.01); A61K 47/64 (2017.01); A61P 25/00 (2006.01); A61K 9/00 (2006.01); A61K 9/70 (2006.01); A61K 47/18 (2017.01); A61L 27/18 (2006.01); A61L 27/22 (2006.01); A61L 27/24 (2006.01); A61L 27/56 (2006.01);
U.S. Cl.
CPC ...
A61K 38/39 (2013.01); A61K 9/0024 (2013.01); A61K 9/70 (2013.01); A61K 47/183 (2013.01); A61K 47/58 (2017.08); A61K 47/6435 (2017.08); A61L 27/18 (2013.01); A61L 27/227 (2013.01); A61L 27/24 (2013.01); A61L 27/56 (2013.01); A61P 25/00 (2018.01); A61L 2430/32 (2013.01);
Abstract

A polyacrylonitrile (PANi) based pharmaceutical composition providing a porous implant for use in treating spinal cord trauma and/or spinal cord injury. Particularly a pharmaceutical composition including polyacrylonitrile (PANi) and/or elastin (E) and/or collagen (C) to form a PANi-E and/or PANi-C and/or a PANi-EC polymer network. Particularly, a pharmaceutical composition including polyacrylonitrile (PANi), elastin (E), and collagen (C) together forming a polyacrylonitrile (PANi), elastin (E), collagen (C) polymer network (PANi-E-C), wherein the polyacrylonitrile (PANi) may be crosslinked to form a crosslinked interpenetrating polyacrylonitrile (PANi), elastin (E) and collagen (C) polymer network (xpi-PANi-E-C), and wherein secondary protein structures of elastin (E) and collagen (C) reorientate. The disclosure extends to use of the pharmaceutical composition in the treatment of spinal cord trauma and/or spinal cord injury.


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