The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 30, 2024

Filed:

Nov. 08, 2017
Applicant:

Musc Foundation for Research Development, Charleston, SC (US);

Inventors:

Shikhar Mehrotra, Mount Pleasant, SC (US);

Shilpak Chatterjee, Charleston, SC (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); A61P 35/00 (2006.01); A61K 35/26 (2015.01); C07K 16/24 (2006.01); C12N 5/0783 (2010.01); A61K 45/06 (2006.01); A61K 9/00 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); A61K 9/0019 (2013.01); A61K 35/26 (2013.01); A61K 39/39558 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07K 16/249 (2013.01); C07K 16/2896 (2013.01); C07K 16/30 (2013.01); C12N 5/0636 (2013.01); C12N 5/0638 (2013.01); C07K 2317/55 (2013.01); C07K 2317/76 (2013.01); C12N 2501/15 (2013.01); C12N 2501/2301 (2013.01); C12N 2501/2306 (2013.01); C12N 2501/2312 (2013.01); C12N 2501/2323 (2013.01); C12N 2501/599 (2013.01);
Abstract

The present disclosure provides methods of producing hybrid Th1/Th17 cells. Also provided herein are methods of treating cancer comprising targeting the CD38-mediated metabolic axis.


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