The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 30, 2024

Filed:

Oct. 21, 2020
Applicant:

Enlivex Therapeutics Rdo Ltd, Nes-Ziona, IL;

Inventors:

Dror Mevorach, Jerusalem, IL;

Shai Novik, Ramat Hasharon, IL;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/15 (2015.01); A61K 39/00 (2006.01); C12N 5/078 (2010.01); A61K 35/17 (2015.01); A61P 37/00 (2006.01); A61K 9/00 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
A61K 35/15 (2013.01); A61K 9/0019 (2013.01); A61K 35/17 (2013.01); A61K 39/0008 (2013.01); A61P 37/00 (2018.01); C12N 5/0634 (2013.01); A61K 2035/122 (2013.01); A61K 2039/515 (2013.01); A61K 2039/58 (2013.01); C12N 2501/39 (2013.01);
Abstract

Cell preparations comprising a pooled and enriched, mononuclear apoptotic cell population, and a method of preparing this cell preparation are described. The pooled mononuclear apoptotic cell preparation may be obtained from pooled, allogeneic white blood cell fractions that are pooled prior to or following induction of apoptosis. Further, described herein are methods of use of these pooled apoptotic cell preparations for treating an immune disease, an inflammatory disease, an autoimmune disease, or infertility in a subject. For example, a pooled apoptotic cell preparation may be used to treat graft versus host disease (GVHD) in an allogeneic subject.


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