The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 30, 2024

Filed:

Jul. 27, 2022
Applicant:

Akebia Therapeutics, Inc., Cambridge, MA (US);

Inventors:

Richard Masaru Kawamoto, Divide, CO (US);

Shengde Wu, West Chester, OH (US);

Artem G. Evdokimov, Foristell, MO (US);

Kenneth D Greis, Fort Thomas, KY (US);

Angelique Sun Boyer, West Chester, OH (US);

Namal C. Warshakoon, Cary, NC (US);

Assignee:

Akebia Therapeutics, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 213/81 (2006.01); C07D 213/65 (2006.01); A61K 31/4418 (2006.01); C07C 235/60 (2006.01); C07C 237/42 (2006.01); C07C 255/57 (2006.01); C07D 405/10 (2006.01); C07D 405/04 (2006.01); C07D 295/192 (2006.01); C07D 401/04 (2006.01); C07D 401/10 (2006.01); C07D 417/04 (2006.01); A61K 31/4433 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4418 (2013.01); A61K 31/4433 (2013.01); C07C 235/60 (2013.01); C07C 237/42 (2013.01); C07C 255/57 (2013.01); C07D 213/65 (2013.01); C07D 213/81 (2013.01); C07D 295/192 (2013.01); C07D 401/04 (2013.01); C07D 401/10 (2013.01); C07D 405/04 (2013.01); C07D 405/10 (2013.01); C07D 417/04 (2013.01); Y02A 50/30 (2018.01);
Abstract

The present disclosure relates to HIF-1α prolyl hydroxylase inhibitors, compositions which comprise the HIF-1α prolyl hydroxylase inhibitors described herein and to methods for controlling, inter alia, Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, and anemia.


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