The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 30, 2024
Filed:
May. 12, 2017
The Regents of the University of Michigan, Ann Arbor, MI (US);
Jolanta Grembecka, Ann Arbor, MI (US);
Tomasz Cierpicki, Ann Arbor, MI (US);
David Rogawski, Ann Arbor, MI (US);
Dmitry Borkin, Ann Arbor, MI (US);
Szymon Klossowski, Ann Arbor, MI (US);
Zhuang Jin, Ann Arbor, MI (US);
Deanna Montgomery, Ann Arbor, MI (US);
Jing Deng, Ann Arbor, MI (US);
Marta Krotoska, Ann Arbor, MI (US);
Hao Li, Ann Arbor, MI (US);
The Regents of the University of Michigan, Ann Arbor, MI (US);
Abstract
Provided herein are small molecule inhibitors of ASH1L activity and small molecules that facilitate ASH1L degradation and methods of use thereof for the treatment of disease, including acute leukemia, solid cancers and other diseases dependent on activity of ASH1L.