The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 23, 2024
Filed:
Mar. 09, 2022
Applicant:
Brown University, Providence, RI (US);
Inventor:
John Marshall, Barrington, RI (US);
Assignee:
Brown University, Providence, RI (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/52 (2006.01); A61P 25/28 (2006.01); A61P 9/10 (2006.01); A61P 25/22 (2006.01); A61P 25/24 (2006.01);
U.S. Cl.
CPC ...
C07K 7/52 (2013.01); A61P 9/10 (2018.01); A61P 25/22 (2018.01); A61P 25/24 (2018.01); A61P 25/28 (2018.01);
Abstract
The present invention provides to compositions and methods useful in the treatment of neurological disorders including, but not limited to, Angelman syndrome, depression, traumatic brain injury, stroke, and Alzheimer's disease. CN2097, a rationally designed cyclic peptidomimetic drug that has been demonstrated to have effectiveness in preclinical models for the treatment of neurological disorders, is rapidly cleared and has a short half-life. The present invention provides a stable analog of CN2097.