The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 23, 2024

Filed:

Jan. 14, 2021
Applicant:

Veroscience Llc, Tiverton, RI (US);

Inventor:

Anthony H. Cincotta, Tiverton, RI (US);

Assignee:

VeroScience LLC, Tiverton, RI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/48 (2006.01); C07D 457/06 (2006.01); A61K 31/4985 (2006.01); C07D 498/14 (2006.01); C07C 59/265 (2006.01);
U.S. Cl.
CPC ...
C07D 457/06 (2013.01); A61K 31/48 (2013.01); A61K 31/4985 (2013.01); C07C 59/265 (2013.01); C07D 498/14 (2013.01);
Abstract

Bromocriptine citrate administered to a vertebrate, animal or human, can be used for any purpose including, e.g., the long-term modification and regulation of metabolic disorders, including prediabetes, obesity, insulin resistance, hyperinsulinemia, hyperglycemia and type 2 diabetes mellitus (T2DM) and/or, e.g., the treatment of other medical disorder(s) including immune or endocrine disorders or diseases. Bromocriptine citrate is administered over a limited or extended period at a time of day dependent on re-establishing the normal circadian rhythm of central dopaminergic activity of healthy members of a similar species and sex. Insulin resistance, hyperinsulinemia and hyperglycemia, T2DM, prediabetes, MS or all, can be controlled in humans on a long term basis by such treatment inasmuch as the daily administration of bromocriptine citrate resets neuronal activity timing in the neural centers of the brain to produce long term effects.


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