The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 23, 2024
Filed:
Feb. 15, 2021
89bio Ltd, Herzliya, IL;
Nadine C. Becknell, Coatesville, PA (US);
Reddeppa Reddy Dandu, Downingtown, PA (US);
Bruce D. Dorsey, Ambler, PA (US);
Dimitar B. Gotchev, Hatboro, PA (US);
Robert L. Hudkins, Chester Springs, PA (US);
Linda Weinberg, King Of Prussia, PA (US);
Craig A. Zificsak, Downington, PA (US);
89BIO LTD, Herzliya, IL;
Abstract
Described herein are 1,4-substituted piperidine compounds according to Formula I that have demonstrated activity as fatty acid synthase inhibitors. Also described herein are pharmaceutical compositions containing the described 1,4-substituted piperidine compounds. Also described herein are methods of treating diseases mediated by fatty acid synthase, by administering one or more of the compounds or pharmaceutical formulations described herein. Also described herein are methods of synthesizing the described 1,4-substituted piperidine compounds and synthetic intermediates useful in those syntheses.