The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 23, 2024

Filed:

Apr. 05, 2019
Applicant:

North Carolina State University, Raleigh, NC (US);

Inventors:

Ashley Brown, Raleigh, NC (US);

Michael Daniele, Raleigh, NC (US);

Jeremy Nortey, Raleigh, NC (US);

Daniel Chester, Raleigh, NC (US);

Terrika Ngobili, Raleigh, NC (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/26 (2006.01); B33Y 10/00 (2015.01); B33Y 70/00 (2020.01); B29C 64/112 (2017.01); A61L 26/00 (2006.01); A61L 27/38 (2006.01); A61L 27/52 (2006.01); B33Y 80/00 (2015.01); B29K 105/00 (2006.01); B29L 31/00 (2006.01);
U.S. Cl.
CPC ...
A61L 27/26 (2013.01); A61L 26/008 (2013.01); A61L 26/0052 (2013.01); A61L 27/3804 (2013.01); A61L 27/52 (2013.01); B29C 64/112 (2017.08); B33Y 10/00 (2014.12); B33Y 70/00 (2014.12); A61L 2300/802 (2013.01); A61L 2400/12 (2013.01); B29K 2105/0061 (2013.01); B29K 2995/0056 (2013.01); B29L 2031/753 (2013.01); B33Y 80/00 (2014.12);
Abstract

Bio-ink compositions comprising bio-compatible microgels or nanogels are described. The bio-inks can comprise, for example, micro- or nanogels comprising crosslinked poly(N-isopropylacrylamide) (poly-NIPam). The bio-inks can further comprise viscosity control agents, such as poly(ethylene glycol) (PEG), and/or surface tension agents. Three-dimensional (3D) printing (e.g., piezoelectric printing) of the bio-inks can provide 3D printed materials comprising microgel or nanogel assemblies of the bio-ink compositions. These materials can be used as scaffolds for preparing biological tissues for use, for instance, in regenerative medicine.


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