The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 23, 2024

Filed:

May. 31, 2018
Applicant:

University of Ulster, Newtownabbey Antrim, GB;

Inventors:

John Callan, Newtownabbey Antrim, GB;

Anthony Mchale, Newtownabbey Antrim, GB;

Sukanta Kamila, Newtownabbey Antrim, GB;

Keiran Logan, Newtownabbey Antrim, GB;

Assignee:

UNIVERSITY OF ULSTER, Newtownabbey Antrim, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/69 (2017.01); A61K 41/00 (2020.01); A61K 47/54 (2017.01); A61K 47/55 (2017.01); A61P 35/00 (2006.01); A61K 31/337 (2006.01); A61K 31/7048 (2006.01); A61K 31/7068 (2006.01); A61K 47/24 (2006.01);
U.S. Cl.
CPC ...
A61K 41/0033 (2013.01); A61K 31/337 (2013.01); A61K 31/7048 (2013.01); A61K 31/7068 (2013.01); A61K 41/0042 (2013.01); A61K 47/24 (2013.01); A61K 47/542 (2017.08); A61K 47/549 (2017.08); A61K 47/55 (2017.08); A61K 47/557 (2017.08); A61K 47/558 (2017.08); A61K 47/6925 (2017.08); A61P 35/00 (2018.01);
Abstract

The invention relates to microbubble complexes for use in methods of sonodynamic therapy which comprise a microbubble attached to or otherwise associated with one or more linking groups, each linking group being bound to at least one sonosensitising agent and at least one chemotherapeutic agent. It further relates to the microbubble complexes themselves and to pharmaceutical compositions which contain them. The invention is particularly suitable for the treatment of deep-sited tumors, in particular pancreatic cancer.


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