The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 23, 2024

Filed:

Jan. 27, 2020
Applicants:

Lentigentechnology, Inc., Gaithersburg, MD (US);

The U.s.a., As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);

Inventors:

Rimas J. Orentas, Seattle, WA (US);

Dina Schneider, Potomac, MD (US);

Boro Dropulic, Ellicott City, MD (US);

Dimiter S. Dimitrov, Frederick, MD (US);

Zhongyu Zhu, Frederick, MD (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); C12N 15/31 (2006.01); C07K 14/47 (2006.01); A61K 35/17 (2015.01); A61K 39/00 (2006.01); C07K 16/28 (2006.01); C07K 14/705 (2006.01); C07K 14/725 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/001113 (2018.08); A61P 35/00 (2018.01); C07K 14/7051 (2013.01); C07K 14/70517 (2013.01); C07K 14/70578 (2013.01); C07K 16/2803 (2013.01); A61K 2039/505 (2013.01); A61K 2039/5156 (2013.01); A61K 2039/5158 (2013.01); C07K 2317/21 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C07K 2319/00 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C07K 2319/33 (2013.01);
Abstract

Chimeric antigen receptors (CARs) containing CD22 antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the CARs are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making CAR T cells are also disclosed.


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