The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 23, 2024
Filed:
Jun. 12, 2020
Applicant:
Agios Pharmaceuticals, Inc., Cambridge, MA (US);
Inventors:
Varsha Venkatachalam Iyer, Boston, MA (US);
Chandra Agarwal Prakash, North Andover, MA (US);
Hua Yang, Acton, MA (US);
Assignee:
Agios Pharmaceuticals, Inc., Cambridge, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/45 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 38/45 (2013.01); A61K 45/06 (2013.01); C12Y 207/0104 (2013.01);
Abstract
Described herein are methods of treating pyruvate kinase deficiency (PKD), sickle cell disease or thalassemia with mitapivat or a pharmaceutically acceptable salt thereof, or use of the drug for the treatment of these conditions, in combination with or in the absence of with a secondary drug, such as an inducer or an inhibitor of cytochrome P450. Various doses and dosing regimens of mitapivat in monotherapy and in concomitant medications are described.