The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 23, 2024
Filed:
Jan. 03, 2019
Applicant:
Sapience Therapeutics, Inc., Harrison, NY (US);
Inventors:
Barry Jay Kappel, Pelham, NY (US);
Gene Merutka, Phoenixville, PA (US);
Jimmy Andrew Rotolo, Port Washington, NY (US);
Assignee:
Sapience Therapeutics, Inc., Tarrytown, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); C07K 14/47 (2006.01); C12N 15/85 (2006.01); A61P 35/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/17 (2013.01); A61P 35/00 (2018.01); C07K 14/47 (2013.01); C07K 14/4705 (2013.01); C12N 15/85 (2013.01); A61K 38/00 (2013.01); C07K 2319/73 (2013.01);
Abstract
Provided are ATF5 peptides having a truncated ATF5 leucine zipper region and, optionally, a cell-penetrating region, compositions comprising the ATF5 peptides, and methods of inhibiting proliferation of and promoting cytotoxicity in a neoplastic cell using the ATF5 peptides.