The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 23, 2024
Filed:
Jun. 23, 2021
Wista Laboratories Ltd., Singapore, SG;
Claude Michel Wischik, Aberdeen, GB;
John Mervyn David Storey, Old Aberdeen, GB;
Colin Marshall, Old Aberdeen, GB;
James Peter Sinclair, Old Aberdeen, GB;
Thomas Craven Baddeley, Old Aberdeen, GB;
WisTa Laboratories Ltd., Singapore, SG;
Abstract
Disclosed are methods of synthesis and/or purification of certain 3,7-diamino-phenothiazin-5-ium compounds ('diaminophenothiazinium compounds') including Methylthioninium Chloride (MTC) (Methylene Blue), and the resulting high purity characterized by a purity greater than 98%, and very low levels of heavy metals and organic impurities Azure A, B, C and MVB. Also disclosed are methods of treatment of a tauopathy or methemoglobinemia in a patient in need thereof, comprising administering to the patient a therapeutically effective amount of the high-purity diaminophenothiazinium compound.