The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 16, 2024
Filed:
Apr. 29, 2021
Applicant:
Morehouse School of Medicine, Atlanta, GA (US);
Inventors:
Gale W. Newman, Duluth, GA (US);
James W. Lillard, Jr., Smyrna, GA (US);
Chamberlain Obialo, Atlanta, GA (US);
Assignee:
Morehouse School of Medicine, Atlanta, GA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/12 (2006.01); G01N 33/68 (2006.01); G01N 33/74 (2006.01); A61K 31/4025 (2006.01); A61K 45/06 (2006.01); A61K 9/00 (2006.01); A61K 31/40 (2006.01); A61K 31/422 (2006.01); A61K 31/505 (2006.01); A61K 31/506 (2006.01); C12Q 1/6883 (2018.01); G01N 33/569 (2006.01); G01N 33/78 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); A61K 9/0019 (2013.01); A61K 31/40 (2013.01); A61K 31/4025 (2013.01); A61K 31/422 (2013.01); A61K 31/505 (2013.01); A61K 31/506 (2013.01); A61K 38/12 (2013.01); A61K 45/06 (2013.01); C12Q 1/6883 (2013.01); G01N 33/56988 (2013.01); G01N 33/74 (2013.01); G01N 33/78 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/5754 (2013.01); G01N 2800/28 (2013.01); G01N 2800/347 (2013.01); G01N 2800/52 (2013.01);
Abstract
The present application relates to methods of treating HIV-associated nephropathy (HIVAN) and/or focal segmental glomerulosclerosis (FSGS) using endothelin-1 (ET-1) antagonists. The application further relates to a composition for the treatment of HIVAN and/or FSGS. A kit for detecting the presence of ET-1 or ET-1-associated biomarker in a biological sample is also disclosed.