The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 16, 2024

Filed:

Aug. 23, 2018
Applicant:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Inventors:

Martin Hund, Horw, CH;

Edelgard Anna Kaiser, Huenenberg See, CH;

Ursula-Henrike Wienhues-Thelen, Krailling, DE;

Dirk Block, Bichl, DE;

Johann Karl, Peissenberg, DE;

Assignee:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 31/00 (2006.01); G01N 33/53 (2006.01); G01N 33/68 (2006.01); G16B 99/00 (2019.01); G16B 20/00 (2019.01); G16B 25/10 (2019.01);
U.S. Cl.
CPC ...
G01N 33/689 (2013.01); G01N 33/6893 (2013.01); G16B 20/00 (2019.02); G16B 25/10 (2019.02); G16B 99/00 (2019.02); G01N 2333/4703 (2013.01); G01N 2333/4745 (2013.01); G01N 2800/368 (2013.01); G01N 2800/52 (2013.01); G01N 2800/60 (2013.01);
Abstract

The present disclosure relates to a method for diagnosing preeclampsia or a preeclampsia-related condition in a pregnant subject. The method is based on the measurement of the amount of the biomarker IGFBP-7 (Insulin-like Growth Factor Binding Protein 7) in a sample from the subject and on the comparison of the measured amount to a reference. Also disclosed are methods for assessing the severity of preeclampsia or a preeclampsia-related condition and methods for monitoring a preeclampsia or a preeclampsia-related condition in a pregnant subject. The present disclosure further relates to the use of the biomarker IGFBP-7 or of an agent that specifically binds to IGFBP-7 in a sample from a pregnant subject for diagnosing, for monitoring or for assessing the severity of preeclampsia or a preeclampsia-related condition. Finally, the present disclosure relates to a device or kit adapted to carry out the method of the present invention.


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