The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 16, 2024
Filed:
Aug. 29, 2020
Mohammad Abdolahad, Tehran, IR;
Mohammad Saeid Nik Shoar, Tehran, IR;
Mahsa Faramarzpour Darzini, Tehran, IR;
Mohammad Abdolahad, Tehran, IR;
Mohammad Saeid Nik Shoar, Tehran, IR;
Mahsa Faramarzpour Darzini, Tehran, IR;
Abstract
A method for fabricating a biosensor for metastasis diagnosis. The method includes coating a photoresist layer on a substrate layer, forming a patterned region by patterning the photoresist layer utilizing a photolithography process, forming a nano-roughened patterned region by forming a plurality of nano-features on the patterned region, stripping the photoresist layer from the substrate layer, forming an array of microelectrodes and a corresponding array of electrical connections on the nano-roughened patterned region by depositing a gold/titanium (Au/Ti) bilayer on the substrate layer with the nano-roughened patterned region and forming a metastatic cell sensing trap on at least one microelectrode of the array of microelectrodes. Where, forming the metastatic cell sensing trap includes placing a solution of Human Umbilical Vein Endothelial Cells (HUVECs) on the biosensor and forcing an attachment between at least one HUVEC of the HUVECs and the at least one microelectrode on the biosensor.