The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 16, 2024

Filed:

Mar. 09, 2018
Applicants:

Veracyte Sd, Inc., San Diego, CA (US);

The Regents of the University of Michigan, Ann Arbor, MI (US);

Inventors:

Elai Davicioni, La Jolla, CA (US);

Nicholas Erho, Vancouver, CA;

Shuang G. Zhao, Ann Arbor, MI (US);

S. Laura Chang, Ann Arbor, MI (US);

Felix Y. Feng, Ann Arbor, MI (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/6886 (2018.01); G16B 5/00 (2019.01); G06N 3/00 (2023.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); G06N 3/00 (2013.01); G16B 5/00 (2019.02); C12Q 2600/106 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/158 (2013.01);
Abstract

The present invention relates to methods, systems and kits for the diagnosis, prognosis and the determination of progression of cancer in a subject. The invention also provides biomarkers that define subgroups of prostate cancer, clinically useful classifiers for distinguishing prostate cancer subtypes, bioinformatic methods for determining clinically useful classifiers, and methods of use of each of the foregoing. The methods, systems and kits can provide expression-based analysis of biomarkers for purposes of subtyping prostate cancer in a subject. Further disclosed herein, in certain instances, are probe sets for use in subtyping prostate cancer in a subject. Classifiers for subtyping a prostate cancer are provided. Methods of treating cancer based on molecular subtyping are also provided.


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