The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 16, 2024
Filed:
Jan. 14, 2019
Applicant:
Laboratory Corporation of America Holdings, Burlington, NC (US);
Inventors:
Stephen Erickson, White Bear Township, MN (US);
Jose S. Gil, Winnetka, CA (US);
Minh Mindy Bao Nguyen, Shoreview, MN (US);
Dwight Lyman Anderson, Minneapolis, MN (US);
Jessica Stach, St. Paul, MN (US);
Assignee:
Laboratory Corporation of America Holdings, Burlington, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/10 (2006.01); C12N 15/86 (2006.01); C12N 15/65 (2006.01); C12Q 1/70 (2006.01); G01N 33/50 (2006.01); C12Q 1/66 (2006.01); A61K 35/76 (2015.01); C12N 15/74 (2006.01); C12N 7/00 (2006.01); C12Q 1/6897 (2018.01); C12Q 1/02 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/10 (2013.01); A61K 35/76 (2013.01); C12N 7/00 (2013.01); C12N 15/65 (2013.01); C12N 15/74 (2013.01); C12N 15/86 (2013.01); C12Q 1/025 (2013.01); C12Q 1/66 (2013.01); C12Q 1/6897 (2013.01); C12Q 1/70 (2013.01); G01N 33/50 (2013.01); C12N 2795/00021 (2013.01); C12N 2795/00031 (2013.01); C12N 2795/00051 (2013.01); C12N 2795/10131 (2013.01); C12N 2795/10143 (2013.01); C12Q 2304/60 (2013.01); G01N 2800/52 (2013.01);
Abstract
Disclosed herein are methods and systems for rapid detection of microorganisms in a sample. A genetically modified bacteriophage is also disclosed which comprises an indicator gene in the late gene region. The specificity of the bacteriophage, such as-specific bacteriophage, allows detection of a specific microorganism, such asspp. and an indicator signal may be amplified to optimize assay sensitivity.