The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 16, 2024
Filed:
Nov. 22, 2017
Applicant:
Wave Life Sciences Ltd., Singapore, SG;
Inventors:
David Charles Donnell Butler, Medford, MA (US);
Pachamuthu Kandasamy, Belmont, MA (US);
Subramanian Marappan, Acton, MA (US);
Ik-Hyeon Paik, Needham, MA (US);
Jayakanthan Kumarasamy, Arlington, MA (US);
Gopal Reddy Bommineni, Belmont, MA (US);
Assignee:
WAVE LIFE SCIENCES LTD., Singapore, SG;
Primary Examiner:
Int. Cl.
CPC ...
C07H 1/06 (2006.01); C07H 19/10 (2006.01); C07H 19/207 (2006.01); C07H 21/00 (2006.01);
U.S. Cl.
CPC ...
C07H 1/06 (2013.01); C07H 19/10 (2013.01); C07H 19/207 (2013.01); C07H 21/00 (2013.01);
Abstract
The present disclosure, among other things, provides technologies for oligonucleotide synthesis. In some embodiments, the present disclosure provides phosphoramidites and methods for synthesis thereof. In some embodiments, provided methods provides higher yields and/or purities. In some embodiments, provided methods remove byproducts without contact with an aqueous solution.