The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 16, 2024

Filed:

May. 02, 2022
Applicant:

Petra Pharma Corporation, New York, NY (US);

Inventors:

Erin Danielle Anderson, Arvada, CO (US);

Sean Douglas Aronow, Boulder, CO (US);

Nicholas A. Boyles, Hillsboro, OR (US);

Surendra Dawadi, Longmont, CO (US);

Eugene R. Hickey, Danbury, CT (US);

Thomas Combs Irvin, Erie, CO (US);

Edward A. Kesicki, New York, NY (US);

Gabrielle R. Kolakowski, Durango, CO (US);

Jennifer Lynn Knight, Jersey City, NJ (US);

Manoj Kumar, Broomfield, CO (US);

Katelyn Frances Long, Lafayette, CO (US);

Christopher Glenn Mayne, Boulder, CO (US);

Alfredo Picado, Superior, CO (US);

Gerit Maria Pototschnig, San Diego, CA (US);

Michael Brian Welch, Westminster, CO (US);

Tien Widjaja, Lafayette, CO (US);

Xiaohong Chen, Broomfield, CO (US);

Nathan Edward Wright, San Diego, CA (US);

Hua-Yu Wang, Chula Vista, CA (US);

Assignee:

PETRA PHARMA CORPORATION, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/10 (2006.01); A61P 35/00 (2006.01); C07D 311/30 (2006.01); C07D 405/12 (2006.01); C07D 407/04 (2006.01); C07D 413/10 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
C07D 405/10 (2013.01); A61P 35/00 (2018.01); C07D 311/30 (2013.01); C07D 405/12 (2013.01); C07D 407/04 (2013.01); C07D 413/10 (2013.01); C07D 417/12 (2013.01);
Abstract

The disclosure relates to compounds of Formula (I) as allosteric chromenone inhibitors of phosphoinositide 3-kinase (PI3K) useful in the treatment of diseases or disorders associated with PI3K modulation, Formula (I): or pharmaceutically acceptable salts thereof wherein R, R, R, R, R, R, R, R, and R, are as defined herein. The disclosure also relates to methods of making and using compounds of Formula (I) or pharmaceutically acceptable salts thereof.


Find Patent Forward Citations

Loading…