The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 16, 2024

Filed:

Feb. 01, 2019
Applicant:

Myokardia, Inc., Brisbane, CA (US);

Inventors:

Sunil Sharma, Gurgaon, IN;

Dinesh Jangid, Gurgaon, IN;

Priyanka Dhaka, Gurgaon, IN;

Siddharth Madhwal, Gurgaon, IN;

Bharat Kumar, Gurgaon, IN;

Kapil Kumar, Gurgaon, IN;

Rajdeep Anand, Gurgaon, IN;

Anurag Jain, Gurgaon, IN;

Assignee:

MyoKardia, Inc., Brisbane, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 231/12 (2006.01); C07D 231/18 (2006.01); B01J 23/72 (2006.01); B01J 27/122 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); B01J 23/72 (2013.01); B01J 27/122 (2013.01); C07D 231/12 (2013.01); C07D 231/18 (2013.01);
Abstract

The present invention provides processes for preparation of substituted pyrazole compounds of formula II, that can be used as intermediates for preparation of substituted piperidine urea compounds useful for the treatment of dilated cardiomyopathy (DCM). Ris independently selected from F, C1-C4 alkyl, C1-C4 haloalkyl, Ris independently selected from H, F, C1-C4 alkyl, C1-C4 haloalkyl, Ris C1-C4 alkyl, Ris H or a protecting group and Ris selected from H, CI or trialkylsilyl.


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