The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 16, 2024

Filed:

May. 26, 2016
Applicants:

The University Court of the University of Glasgow, Glasgow, GB;

Georgia Tech Research Corporation, Atlanta, GA (US);

Inventors:

Manuel Salmeron-Sanchez, Glasgow, GB;

Matthew J. Dalby, Glasgow, GB;

Andres J. Garcia, Atlanta, GA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/36 (2006.01); A61L 27/22 (2006.01); A61L 27/54 (2006.01); A61K 38/18 (2006.01); A61L 27/34 (2006.01);
U.S. Cl.
CPC ...
A61L 27/225 (2013.01); A61K 38/1825 (2013.01); A61K 38/1841 (2013.01); A61K 38/1866 (2013.01); A61K 38/1875 (2013.01); A61L 27/227 (2013.01); A61L 27/34 (2013.01); A61L 27/54 (2013.01); A61L 2300/414 (2013.01); A61L 2300/426 (2013.01); A61L 2400/18 (2013.01);
Abstract

The invention provides materials presenting a biologically active matrix comprising a physiological fibrillar fibronectin network, such as implantable constructs, and their use for modulating cell behaviour and fate, including cell growth, proliferation and/or differentiation, such as for promoting tissue regeneration, for example, bone regeneration or vascularization. Also provided are constructs presenting a biologically active matrix comprising a physiological fibrillar fibronectin network for sustaining growth of stem cells or maintaining stem cells (maintaining stemness).


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