The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 16, 2024
Filed:
Dec. 21, 2021
Applicants:
Kyungpook National University Industry-academic Cooperation Foundation, Daegu, KR;
Kyungpook National University Hospital, Daegu, KR;
Inventors:
In Kyu Lee, Daegu, KR;
Eun Jung Choi, Daegu, KR;
Chang Hyun Jeon, Daegu, KR;
Tae-Hwan Kwon, Daegu, KR;
Dong Ho Park, Daegu, KR;
Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/24 (2006.01); C07D 405/12 (2006.01); A61K 31/505 (2006.01); A61K 31/506 (2006.01); A61P 31/00 (2006.01); A61K 31/51 (2006.01);
U.S. Cl.
CPC ...
A61K 31/51 (2013.01);
Abstract
The present disclosure is a pharmaceutical composition for the prevention or treatment of sepsis containing a thiamine derivative or a pharmaceutically acceptable salt thereof, wherein the pharmaceutical composition of the present disclosure can be used for the prevention, alleviation, or treatment of sepsis by containing fursultiamine or allithiamine to inhibit the expressions of CD40, CD86, and TNFα.