The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 16, 2024

Filed:

May. 29, 2020
Applicant:

Ilias Biologics Inc., Daejeon, KR;

Inventors:

Chulhee Choi, Daejeon, KR;

Nambin Yim, Daejeon, KR;

Won Do Heo, Daejeon, KR;

Seung-Wook Ryu, Daejeon, KR;

Hojun Choi, Daejeon, KR;

Kyungsun Choi, Daejeon, KR;

Assignee:

ILIAS BIOLOGICS INC., Daejeon, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/62 (2006.01); C12N 15/85 (2006.01); A61K 47/69 (2017.01); A61K 38/17 (2006.01); C07K 16/28 (2006.01); C12P 21/02 (2006.01); C07K 16/18 (2006.01); C07K 14/705 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/177 (2013.01); A61K 47/6917 (2017.08); C07K 14/705 (2013.01); C07K 14/70596 (2013.01); C07K 16/18 (2013.01); C07K 16/28 (2013.01); C12N 15/62 (2013.01); C12N 15/85 (2013.01); C12P 21/02 (2013.01); A61K 38/00 (2013.01); C07K 2317/80 (2013.01); C07K 2319/03 (2013.01); C07K 2319/70 (2013.01);
Abstract

The present invention relates to a method for the mass-production of exosome comprising a cargo protein, a vector for preparing the exosome, exosome including a cargo protein prepared by the method, and a method for loading the cargo protein to cytosol by using the exosome prepared thereby. According to the method for preparing an exosome comprising a cargo protein provided by the present invention, the exosome loaded with a cargo protein can be produced with a high yield, so that it can be used broadly in the treatment of disease using the exosome.


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