The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 2024
Filed:
Mar. 05, 2019
Applicant:
University of Newcastle Upon Tyne, Newcastle upon Tyne, GB;
Inventors:
Marzena Kurzawa-Akanbi, Newcastle upon Tyne, GB;
Christopher Mile Morris, Newcastle upon Tyne, GB;
Assignee:
UNIVERSITY OF NEWCASTLE UPON TYNE, Newcastle upon Tyne, GB;
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6896 (2013.01); G01N 2800/2835 (2013.01);
Abstract
The present invention provides novel methods of identifying, monitoring or determining the risk of developing a protein misfolding neurodegenerative disorder in a subject, particularly an alpha synucleinopathy (including Parkinson's disease and dementia with Lewy bodies) using extracellular vesicle samples. Corresponding methods for selecting a treatment and assaying for the presence of a pathological prion-like protein (or one or more ceramide species) in an extracellular vesicle sample are also provided.