The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 2024
Filed:
Mar. 25, 2021
Applicant:
Organovo, Inc., San Diego, CA (US);
Inventors:
Deborah Lynn Greene Nguyen, San Diego, CA (US);
Shelby Marie King, San Diego, CA (US);
Sharon C. Presnell, San Diego, CA (US);
Assignee:
ORGANOVO, INC., San Diego, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
G01N 33/5014 (2013.01); C12N 5/0684 (2013.01); C12N 5/0697 (2013.01); G01N 33/5044 (2013.01); C12N 2502/1323 (2013.01); C12N 2502/256 (2013.01); C12N 2502/28 (2013.01); G01N 2500/02 (2013.01); G01N 2500/10 (2013.01);
Abstract
Disclosed are renal tissues and arrays thereof that include a layer of renal interstitial tissue, the renal interstitial tissue comprising renal fibroblasts and endothelial cells; and a layer of renal epithelial tissue, the renal epithelial tissue comprising renal tubular epithelial cells, the renal epithelial tissue in contact with the layer of renal interstitial tissue to form a three-dimensional, engineered, biological renal tissue. Also disclosed are methods of fabricating and using the same.